Skype for Business on Mac High Sierra Hi I like many others it seems am no longer able to use Skype for Business after upgrading my Mac OS to High Sierra, it did work, but as of today will not open, I have uninstalled and reinstalled the app but that has not resolved the issue. How do I join a Skype for Business meeting on a Mac? You can join a meeting right from the Skype for Business on Mac main window, without having to go to Outlook. Need to upgrade your operating system? See other system requirements. To find out which OS version you have, from the Apple menu, click About This Mac. Skype for Business on Mac runs on OS X El Capitan or later versions. Depending on how your organization is set up, you will use either Skype Meetings App or Skype for Business Web App. If you don’t have the desktop version of Skype for Business, or don’t have a Skype for Business account, you can use Skype Meetings App or Skype for Business Web App to join a Skype for Business meeting from your browser. Check the box next to Safe boot to enable the option, and then also enable the Network option underneath it. Navigate to the Boot tab of System Configuration. Press the Windows Logo key + R to open a Run dialog, type msconfig.exe into the Run dialog and press Enter to launch System Configuration. Solution 2: Try launching and signing in to Skype in Safe Mode.